Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A polymorphism in the delta-aminolevulinic acid dehydratase gene modifies plasma/whole blood lead ratio.

Archives of toxicology - 1 Jul 2006

Montenegro Marcelo F, Barbosa Fernando, Sandrim Valeria C, Gerlach Raquel F, Tanus-Santos Jose E

Abstract excerpt

Delta aminolevulinic acid dehydratase (ALAD) plays an important role in lead poisoning. This study was carried out to examine the effects of ALAD gene polymorphism (G177C) on %Pb-P(plasma lead)/Pb-B(whole blood) ratio in 142 subjects environmentally exposed to lead. Genotypes for the ALAD G177C polymorphism were determined by PCR and restriction fragment length digestion. Pb-P and Pb-B were determined by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Brazil
Share to Environmental Exposure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Polymorphism, Restriction Fragment Length

Share to Porphobilinogen Synthase

Source

Identifiers

PMID: 16341691
DOI: 10.1007/s00204-005-0056-y

Genes

ALAD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A polymorphism in the delta-aminolevulinic acid dehydratase gene modifies plasma/whole blood lead ratio.PMID 16341691Read ↗

Modifying effects of δ-Aminolevulinate dehydratase polymorphism on blood lead levels and ALAD activity.Semantic proximity Read ↗

A study on the ALAD gene polymorphisms associated with lead exposure.Semantic proximity Read ↗

Genetic susceptibility of δ-ALAD associated with lead (Pb) intoxication: sources of exposure, preventive measures, and treatment interventions.Semantic proximity Read ↗

Association between delta-aminolevulinic acid dehydratase polymorphism and placental lead levels.Semantic proximity Read ↗

Delta-aminolevulinic acid dehydratase genotype and lead toxicity: a HuGE review.Semantic proximity Read ↗

δ-Aminolevulinic acid dehydratase genotype predicts toxic effects of lead on workers' peripheral nervous system.Semantic proximity Read ↗

Delta-aminolevulinate dehydratase polymorphism and blood lead levels in Chinese children.Semantic proximity Read ↗

Use of Generalized Additive Model to Detect the Threshold of δ-Aminolevulinic Acid Dehydratase Activity Reduced by Lead Exposure.Semantic proximity Read ↗

Relationship between delta-aminolevulinic acid dehydratase genotypes and heme precursors in lead workers.Semantic proximity Read ↗

Investigation of delta-aminolevulinic acid dehydratase polymorphism affecting hematopoietic, hepatic and renal toxicity from lead in Han subjects of southwestern China.Semantic proximity Read ↗

Lead and delta-aminolevulinic acid dehydratase polymorphism: where does it lead? A meta-analysis.Semantic proximity Read ↗

Influence of delta-aminolevulinic acid dehydratase gene polymorphism on selected lead exposure biomarkers in a cohort of ex-smelter workers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.