Article
Synaptic homeostasis is consolidated by the cell fate gene gooseberry, a Drosophila pax3/7 homolog.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 16 Jun 2010
Marie Bruno, Pym Edward, Bergquist Sharon, Davis Graeme W
Abstract excerpt
In a large-scale screening effort, we identified the gene gooseberry (gsb) as being necessary for synaptic homeostasis at the Drosophila neuromuscular junction. The gsb gene encodes a pair-rule transcription factor that participates in embryonic neuronal cell fate specification. Here, we define a new postembryonic role for gooseberry. We show that gsb becomes widely expressed in the postembryonic CNS, including...
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