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Article

Spatiotemporal regulation of early lipolytic signaling in adipocytes.

The Journal of biological chemistry - 13 Nov 2009

Martin Sally, Okano Satomi, Kistler Carol, Fernandez-Rojo Manuel A, Hill Michelle M, Parton Robert G

Abstract excerpt

Hormone-sensitive lipase (HSL) is a key enzyme regulating the acute activation of lipolysis. HSL functionality is controlled by multiple phosphorylation events, which regulate its association with the surface of lipid droplets (LDs). We determined the progression and stability of HSL phosphorylation on individual serine residues both spatially and temporally in adipocytes using phospho-specific antibodies. Within...

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Identifiers

PMID: 19755426
DOI: 10.1074/jbc.M109.002675
PMCID: PMC2797280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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