Article
Hormone-sensitive lipase expression and activity in relation to lipolysis in human fat cells.
Journal of lipid research - 1 Aug 1998
Large V, Arner P, Reynisdottir S, Grober J, Van Harmelen V, Holm C, Langin D
Abstract excerpt
Hormone-sensitive lipase (HSL) catalyzes the rate-limiting step in adipocyte lipolysis. The activity of HSL is thought to be primarily regulated by reversible phosphorylation. However, the regulation of HSL activity by pre-translational mechanisms has been poorly studied. The present studies were undertaken to explore the relationship between the levels of HSL protein and mRNA expressions and the lipolytic...
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