Article
Dynamics and molecular determinants of cytoplasmic lipid droplet clustering and dispersion.
PloS one - 1 Jan 2013
Orlicky David J, Monks Jenifer, Stefanski Adrianne L, McManaman James L
Abstract excerpt
Perilipin-1 (Plin1), a prominent cytoplasmic lipid droplet (CLD) binding phosphoprotein and key physiological regulator of triglyceride storage and lipolysis in adipocytes, is thought to regulate the fragmentation and dispersion of CLD that occurs in response to β-adrenergic activation of adenylate cyclase. Here we investigate the dynamics and molecular determinants of these processes using cell lines stably...
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