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Article

Functional interaction of hormone-sensitive lipase and perilipin in lipolysis.

Journal of lipid research - 1 Nov 2009

Shen Wen-Jun, Patel Shailja, Miyoshi Hideaki, Greenberg Andrew S, Kraemer Fredric B

Abstract excerpt

Adipocyte lipolysis is controlled by complex interactions of lipases, cofactors, and structural proteins associated with lipid droplets. Perilipin (Plin) A is a major droplet-associated protein that functions as a scaffold, both suppressing basal and facilitating cAMP-dependent protein kinase (PKA)-stimulated lipolysis. Plin is required for the translocation of hormone-sensitive lipase (HSL) from the cytosol to...

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Identifiers

PMID: 19515989
DOI: 10.1194/jlr.M900176-JLR200
PMCID: PMC2759837

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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