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Article

HECTD2, a candidate susceptibility gene for Alzheimer's disease on 10q.

BMC medical genetics - 15 Sept 2009

Lloyd Sarah E, Rossor Martin, Fox Nick, Mead Simon, Collinge John

Abstract excerpt

BACKGROUND: Late onset Alzheimer's disease (LOAD) is a neurodegenerative disorder characterised by the deposition of amyloid plaques and neurofibrillary tangles in the brain and is the major cause of dementia. Multiple genetic loci, including 10q, have been implicated in LOAD but to date, with the exception of APOE, the underlying genes have not been identified. HECTD2 maps to 10q and has been implicated in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 10

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Source

Open in PubMed Open full text

Identifiers

PMID: 19754925
DOI: 10.1186/1471-2350-10-90
PMCID: PMC2753310

Genes

HECTD2
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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