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Article

Association and heterogeneity at the GAPDH locus in Alzheimer's disease.

Neurobiology of aging - 1 Jan 2012

Allen Mariet, Cox Claire, Belbin Olivia, Ma Li, Bisceglio Gina D, Wilcox Samantha L, Howell Chanley C, Hunter Talisha A, Culley Oliver, Walker Louise P, Carrasquillo Minerva M, Dickson Dennis W, Petersen Ronald C, Graff-Radford Neill R, Younkin Steven G, Ertekin-Taner Nilüfer

Abstract excerpt

Glyceraldehyde-3-phosphate dehydrogenase gene (GAPDH) and its paralogs were implicated in late-onset Alzheimer's disease (LOAD), although the strength and direction of association have not been consistent. We genotyped 3 previously reported single nucleotide polymorphisms (SNPs; rs3741916-GAPDH 5' UTR, rs2029721-pGAPD, and rs4806173-GAPDHS) in 3 case-control series (2112 cases and 3808 controls). Rs3741916 showed...

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Source

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Identifiers

PMID: 20864222
DOI: 10.1016/j.neurobiolaging.2010.08.002
PMCID: PMC3017231

Genes

GAPDH
GAPDHS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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