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Article

The effect of alcohol and tobacco consumption, and apolipoprotein E genotype, on the age of onset in Alzheimer's disease.

International journal of geriatric psychiatry - 1 May 2010

Harwood Dylan G, Kalechstein Ari, Barker Warren W, Strauman Silvia, St George-Hyslop Peter, Iglesias Casandra, Loewenstein David, Duara Ranjan

Abstract excerpt

OBJECTIVE: This study examined the association between a history of heavy alcohol use and smoking, presence of the apolipoprotein-E epsilon 4 allele (APOE epsilon4), and age of disease onset in a community dwelling sample of 685 Alzheimer's disease (AD) patients spanning three ethnic groups. DESIGN: Cross-sectional study of AD patients evaluated at a University-affiliated outpatient memory disorders clinic....

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Source

Identifiers

PMID: 19750560
DOI: 10.1002/gps.2372

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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