APOE genotype effects on Alzheimer's disease onset and epidemiology.

doi:10.1385/JMN:23:3:157

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Article

APOE genotype effects on Alzheimer's disease onset and epidemiology.

Journal of molecular neuroscience : MN - 1 Jan 2004

Ashford J Wesson

Abstract excerpt

The risk of developing Alzheimer's disease (AD) is tied most closely to age and appears to follow Gompertzian kinetics. However, specific genetic factors are also linked closely to AD, and the apolipoprotein E (APOE) genotype accounts for as much of 50% of the attributable risk for AD in many populations. This paper reviews the onset, diagnosis, and epidemiology of AD, specifically with regard to the APOE...

Topics

Age Distribution
Age of Onset
Aged
Alzheimer Disease
Apolipoproteins E
Centers for Disease Control and Prevention, U.S.
Genotype
Humans
Risk Factors
United States

Source

Open in PubMed

Identifiers

PMID: 15181244
DOI: 10.1385/JMN:23:3:157

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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