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Article

Apolipoprotein E epsilon4 and age at onset of sporadic and familial Alzheimer disease in Caribbean Hispanics.

Archives of neurology - 1 Nov 2006

Olarte Lucia, Schupf Nicole, Lee Joseph H, Tang Ming-Xin, Santana Vincent, Williamson Jennifer, Maramreddy Prashanthi, Tycko Benjamin, Mayeux Richard

Abstract excerpt

BACKGROUND: The primary effect of the apolipoprotein E epsilon4 (APOE epsilon4) allele is on the age at onset of Alzheimer disease (AD). OBJECTIVE: To investigate whether the presence of the APOE epsilon4 allele can account for the earlier age at onset of familial AD (FAD) compared with sporadic AD (SAD). DESIGN: Population-based, case series ascertained in a prospective study of aging and dementia in Medicare...

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Source

Identifiers

PMID: 17101827
DOI: 10.1001/archneur.63.11.1586

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Apolipoprotein E epsilon4 and age at onset of sporadic and familial Alzheimer disease in Caribbean Hispanics.PMID 17101827Read ↗

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