Article
Apolipoprotein E and Alzheimer's disease: strength of association is related to age at onset.
Dementia (Basel, Switzerland) - 1 Jan 2000
Murman D L, Foster N L, Kilgore S P, McDonagh C A, Fink J K
Abstract excerpt
Apolipoprotein E (apoE) epsilon 4 allele frequency among Alzheimer's disease (AD) patients is increased compared to control subjects and is influenced by the presence of other genetic factors and age at symptom onset. We examined the relationship between age at AD symptom onset and apoE by comparing the apoE epsilon 4 allele frequency of normal, elderly control subjects (n = 107) to that in AD patients (n = 123),...
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