Article
Apolipoprotein E polymorphism and age of onset for Alzheimer's disease in a bi-ethnic sample.
International psychogeriatrics - 1 Sept 2004
Harwood Dylan G, Barker Warren W, Ownby Raymond L, St George-Hyslop Peter, Mullan Michael, Duara Ranjan
Abstract excerpt
OBJECTIVE: This study examined the association between the Apolipoprotein-E epsilon4 allele (APOE epsilon4) and age of disease onset in a bi-ethnic sample of community dwelling Alzheimer's disease (AD) patients. DESIGN: Cross-sectional study of AD patients evaluated at a University-affiliated outpatient memory disorders clinic. SUBJECTS: A clinic-based cohort of white non-Hispanic (WNH; n=601) and white Hispanic...
Topics
- Age of Onset
- Aged
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Cross-Sectional Studies
- Ethnicity
- Female
- Gene Frequency
- Genotype
- Humans
