Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Apolipoprotein E genotype and association between smoking and early onset Alzheimer's disease.

BMJ (Clinical research ed.) - 11 Mar 1995

van Duijn C M, Havekes L M, Van Broeckhoven C, de Knijff P, Hofman A

Abstract excerpt

OBJECTIVE: To investigate the hypothesis that differential survival between smokers and non-smokers leading to a decrease in the frequency of the e4 allele of the apolipoprotein E gene may explain the inverse relation between smoking history and early onset Alzheimer's disease. DESIGN: A population based case-control study. SETTING: The four northern provinces of the Netherlands and metropolitan Rotterdam....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Alleles
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Apolipoproteins E

Share to Case-Control Studies

Share to Gene Frequency

Share to Heterozygote

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 7703749
DOI: 10.1136/bmj.310.6980.627
PMCID: PMC2549007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Apolipoprotein E genotype and association between smoking and early onset Alzheimer's disease.PMID 7703749Read ↗

Association of apolipoprotein E phenotypes with late onset Alzheimer's disease: population based study.Semantic proximity Read ↗

Relation between smoking and risk of dementia and Alzheimer disease: the Rotterdam Study.Semantic proximity Read ↗

The effect of alcohol and tobacco consumption, and apolipoprotein E genotype, on the age of onset in Alzheimer's disease.Semantic proximity Read ↗

Apolipoprotein E phenotypes, dementia and mortality in a prospective population sample.Semantic proximity Read ↗

Midlife smoking, apolipoprotein E and risk of dementia and Alzheimer's disease: a population-based cardiovascular risk factors, aging and dementia study.Semantic proximity Read ↗

Apolipoprotein E genotype and progression of Alzheimer's disease: the Rotterdam Study.Semantic proximity Read ↗

Alzheimer's disease: interaction of apolipoprotein E genotype, family history of dementia, gender, education, ethnicity, and age of onset.Semantic proximity Read ↗

APOE e4 genotype and cigarette smoking in adults with normal cognition and mild cognitive impairment: a retrospective baseline analysis of a national dataset.Semantic proximity Read ↗

Apolipoprotein E4 allele and Alzheimer disease: examination of allelic association and effect on age at onset in both early- and late-onset cases.Semantic proximity Read ↗

Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease.Semantic proximity Read ↗

[The apolipoprotein E-epsilon 4 allele is a risk factor for Alzheimer disease with early and late onset].Semantic proximity Read ↗

Age stratification corrects bias in estimated hazard of APOE genotype for Alzheimer's diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.