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Article

Isoniazid-resistant Mycobacterium tuberculosis strains arising from mutations in two different regions of the katG gene.

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia - 1 Aug 2009

Siqueira Helio Ribeiro de, Freitas Flávia Alvim Dutra de, Oliveira Denise Neves de, Barreto Angela Maria Werneck, Dalcolmo Margareth Pretti, Albano Rodolpho Mattos

Abstract excerpt

OBJECTIVE: To analyze and compare the mutations in two different regions of the katG gene, which is responsible for isoniazid (INH) resistance. METHODS: We analyzed 97 multidrug-resistant Mycobacterium tuberculosis strains isolated in cultures of sputum samples obtained from the Professor Hélio Fraga Referral Center, in Brasília, Brazil. Another 6 INH-sensitive strains did not present mutations and were included...

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PMID: 19750330
DOI: 10.1590/s1806-37132009000800009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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