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Article

Mutations in katG, inhA, and ahpC genes of Brazilian isoniazid-resistant isolates of Mycobacterium tuberculosis.

Journal of clinical microbiology - 1 Sept 2003

Silva Márcia Susana N, Senna Simone G, Ribeiro Marta O, Valim Andréia R M, Telles Maria Alice, Kritski Afrânio, Morlock Glenn P, Cooksey Robert C, Zaha Arnaldo, Rossetti Maria Lucia R

Abstract excerpt

The presence of mutations in specific regions of the katG, inhA, and ahpC genes was analyzed with 69 Mycobacterium tuberculosis isoniazid-resistant isolates from three Brazilian states. Point mutations in codon 315 of the katG gene were observed in 87.1, 60.9, and 60% of the isolates from Rio Grande do Sul, Rio de Janeiro, and São Paulo, respectively. Mutations in the inhA gene were identified only in one isolate...

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Identifiers

PMID: 12958298
DOI: 10.1128/JCM.41.9.4471-4474.2003
PMCID: PMC193791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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