Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic association of htSNPs across the major histocompatibility complex with rheumatoid arthritis in an African-American population.

Genes and immunity - 1 Jan 2010

Reynolds R J, Kelley J M, Hughes L B, Yi N, Bridges S L

Abstract excerpt

Notwithstanding the well-established association of HLA-DRB1 shared epitope alleles, interest remains in identifying additional major histocompatibility complex (MHC) region variants associated with rheumatoid arthritis (RA). We used a panel of 1201 haplotype-tagging single nucleotide polymorphisms (SNPs) designed for African Americans to find genetic variants associated with RA in a 3.8-Mb region encompassing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Arthritis, Rheumatoid
Share to Black or African American

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Gene Frequency

Share to HLA-D Antigens

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Source

Open in PubMed Open full text

Identifiers

PMID: 19741715
DOI: 10.1038/gene.2009.69
PMCID: PMC2809137

Genes

MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic association of htSNPs across the major histocompatibility complex with rheumatoid arthritis in an African-American population.PMID 19741715Read ↗

Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis.Semantic proximity Read ↗

A genome-wide association study for rheumatoid arthritis replicates previous HLA and non-HLA associations in a cohort from South Africa.Semantic proximity Read ↗

Evaluating linkage disequilibrium and recombination provides a haplotype-tagging SNP panel of the major histocompatibility complex in African Americans.Semantic proximity Read ↗

Most common single-nucleotide polymorphisms associated with rheumatoid arthritis in persons of European ancestry confer risk of rheumatoid arthritis in African Americans.Semantic proximity Read ↗

Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis.Semantic proximity Read ↗

Association of single-nucleotide polymorphisms in CCR6, TAGAP, and TNFAIP3 with rheumatoid arthritis in African Americans.Semantic proximity Read ↗

Genetic influences on susceptibility to rheumatoid arthritis in African-AmericansSemantic proximity Read ↗

Dense Genotyping of Immune-Related Regions Identifies Loci for Rheumatoid Arthritis Risk and Damage in African Americans.Semantic proximity Read ↗

Dissecting the genetic complexity of the association between human leukocyte antigens and rheumatoid arthritis.Semantic proximity Read ↗

Use of a multiethnic approach to identify rheumatoid- arthritis-susceptibility loci, 1p36 and 17q12.Semantic proximity Read ↗

Several regions in the major histocompatibility complex confer risk for anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus.Semantic proximity Read ↗

HLA-DRB1-associated rheumatoid arthritis risk at multiple levels in African Americans: hierarchical classification systems, amino acid positions, and residues.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.