Article
Common genetic determinants of glucose homeostasis in healthy children: the European Youth Heart Study.
Diabetes - 1 Dec 2009
Kelliny Clara, Ekelund Ulf, Andersen Lars Bo, Brage Soren, Loos Ruth J F, Wareham Nicholas J, Langenberg Claudia
Abstract excerpt
OBJECTIVE: The goal of this study was to investigate whether the effects of common genetic variants associated with fasting glucose in adults are detectable in healthy children. RESEARCH DESIGN AND METHODS: Single nucleotide polymorphisms in MTNR1B (rs10830963), G6PC2 (rs560887), and GCK (rs4607517) were genotyped in 2,025 healthy European children aged 9-11 and 14-16 years. Associations with fasting glucose,...
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