Article
Impact of common variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 on the risk of type 2 diabetes in 5,164 Indians.
Diabetes - 1 Aug 2010
Chauhan Ganesh, Spurgeon Charles J, Tabassum Rubina, Bhaskar Seema, Kulkarni Smita R, Mahajan Anubha, Chavali Sreenivas, Kumar M V Kranthi, Prakash Swami, Dwivedi Om Prakash, Ghosh Saurabh, Yajnik Chittaranjan S, Tandon Nikhil, Bharadwaj Dwaipayan, Chandak Giriraj R
Abstract excerpt
OBJECTIVE: Common variants in PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 genes have been shown to be associated with type 2 diabetes in European populations by genome-wide association studies. We have studied the association of common variants in these eight genes with type 2 diabetes and related traits in Indians by combining the data from two independent case-control studies. RESEARCH...
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