Article
The molecular basis of phenotypic variation in yeast.
Current opinion in genetics & development - 1 Dec 2013
Fay Justin C
Abstract excerpt
The power of yeast genetics has now been extensively applied to phenotypic variation among strains of Saccharomyces cerevisiae. As a result, over 100 genes and numerous sequence variants have been identified, providing us with a general characterization of mutations underlying quantitative trait variation. Most quantitative trait alleles exert considerable phenotypic effects and alter conserved amino acid...
Topics
- Alleles
- Chromosome Mapping
- Chromosomes, Fungal
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genetic Variation
- Phenotype
- Quantitative Trait Loci
- Reverse Genetics
- Saccharomyces cerevisiae
