Article
Rare variants contribute disproportionately to quantitative trait variation in yeast
2019-04-15
Abstract excerpt
A detailed understanding of the sources of heritable variation is a central goal of modern genetics. Genome-wide association studies (GWAS) in humans 1 have implicated tens of thousands of DNA sequence variants in disease risk and quantitative trait variation, but these variants fail to account for the entire heritability of diseases and traits. GWAS have by design focused on common DNA sequence variants; however...
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Identifiers and source
- Literature Corpus work
- 30620697-d067-5102-bd96-f88055e438cb
- DOI
- 10.1101/607291