Article
Dissecting the architecture of a quantitative trait locus in yeast.
Nature - 21 Mar 2002
Steinmetz Lars M, Sinha Himanshu, Richards Dan R, Spiegelman Jamie I, Oefner Peter J, McCusker John H, Davis Ronald W
Abstract excerpt
Most phenotypic diversity in natural populations is characterized by differences in degree rather than in kind. Identification of the actual genes underlying these quantitative traits has proved difficult. As a result, little is known about their genetic architecture. The failures are thought to be due to the different contributions of many underlying genes to the phenotype and the ability of different...
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