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Article

The essential role of TNIK gene amplification in gastric cancer growth

24 Feb 2014

Abstract excerpt

Traf2- and Nck-interacting kinase (TNIK) is one of the germinal center kinase family members involved in cytoskeleton organization and neuronal dendrite extension. Emerging evidence supports that TNIK is essential for activation of WNT signaling pathway in colon cancer growth. To search for novel genetic aberrations that drive carcinogenesis, we performed microarray-based comparative hybridization assay for gene...

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PMID: 24566388
DOI: 10.1038/oncsis.2014.2

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