Article
Dynamic regulation of antigen receptor gene assembly.
Advances in experimental medicine and biology - 1 Jan 2009
Thomas Lance R, Cobb Robin Milley, Oltz Eugene M
Abstract excerpt
A hallmark feature of adaptive immunity is the production of lymphocytes bearing an enormous repertoire of receptors for foreign antigens. This repertoire is generated early in B and T-cell development by the process of V(D)J recombination, which randomly assembles functional immunoglobulin (Ig)...
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