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Article

Epigenetic regulation of antigen receptor rearrangement.

Clinical immunology (Orlando, Fla.) - 1 Oct 2003

Inlay Matthew, Xu Yang

Abstract excerpt

In the mammalian immune system, V(D)J rearrangement of immunoglobulin (Ig) and T-cell receptor (TCR) genes is regulated in a lineage- and stage-specific fashion. Because each of the seven loci capable of rearrangement utilizes the same recombination machinery, it is thought that V(D)J recombination of each antigen receptor locus is regulated through the differential accessibility of each locus to the V(D)J...

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Source

Identifiers

PMID: 14585273
DOI: 10.1016/s1521-6616(03)00199-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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