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Article

Proteins and single nucleotide polymorphisms involved in apoptosis, growth control, and DNA repair predict cisplatin sensitivity in head and neck cancer cell lines.

International journal of molecular medicine - 1 Oct 2009

Farnebo Lovisa, Jedlinski Adam, Ansell Anna, Vainikka Linda, Thunell Lena K, Grénman Reidar, Johansson Ann-Charlotte, Roberg Karin

Abstract excerpt

The present study was undertaken to evaluate the possibility of using a panel of proteins and single nucleotide polymorphisms (SNPs) involved in apoptosis, growth control, and DNA repair as predictive markers for cisplatin sensitivity. For this purpose the intrinsic cisplatin sensitivity (ICS) was determined in 39 cell lines derived from squamous cell carcinomas of the head and neck using a colony-forming assay....

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Share to bcl-2-Associated X Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Head and Neck Neoplasms

Share to Proto-Oncogene Proteins c-bcl-2

Share to Proto-Oncogene Proteins c-mdm2

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Share to X-ray Repair Cross Complementing Protein 1

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Source

Identifiers

PMID: 19724896
DOI: 10.3892/ijmm_00000264

Genes

EGFR
XPC
XRCC1
XRCC3
FGFR4
MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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