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Article

Sequence and expression variations in 23 genes involved in mitochondrial and non-mitochondrial apoptotic pathways and risk of oral leukoplakia and cancer.

Mitochondrion - 1 Nov 2015

Datta Sayantan, Ray Anindita, Singh Richa, Mondal Pinaki, Basu Analabha, De Sarkar Navonil, Majumder Mousumi, Maiti Guruparasad, Baral Aradhita, Jha Ganga Nath, Mukhopadhyay Indranil, Panda Chinmay, Chowdhury Shantanu, Ghosh Saurabh, Roychoudhury Susanta, Roy Bidyut

Abstract excerpt

Oral cancer is usually preceded by pre-cancerous lesion and related to tobacco abuse. Tobacco carcinogens damage DNA and cells harboring such damaged DNA normally undergo apoptotic death, but cancer cells are exceptionally resistant to apoptosis. Here we studied association between sequence and expression variations in apoptotic pathway genes and risk of oral cancer and precancer. Ninety nine tag SNPs in 23...

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Share to Apoptosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukoplakia, Oral

Share to Metabolic Networks and Pathways

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Share to Sequence Analysis, DNA

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Source

Identifiers

PMID: 26403071
DOI: 10.1016/j.mito.2015.09.001

Genes

BCL2
CASP1
CASP10
BID
CASP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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