FAS and FASL variations in outcomes of tobacco- and alcohol-related head and neck squamous cell carcinoma patients.

doi:10.1177/1010428320938494

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Article

FAS and FASL variations in outcomes of tobacco- and alcohol-related head and neck squamous cell carcinoma patients.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2020

Costa Ericka Francislaine Dias, Lima Tathiane Regine Penna, Lopes-Aguiar Leisa, Nogueira Guilherme Augusto Silva, Visacri Marília Berlofa, Quintanilha Julia Coelho França, Pincinato Eder Carvalho, Calonga Luciane, Mariano Fernanda Viviane, Altemani Albina Messias de Almeida Milani, Altemani João Maurício Carrasco, Moriel Patrícia, Chone Carlos Takahiro, Ramos Celso Dario, Lima Carmen Silvia Passos

Abstract excerpt

Radiotherapy and cisplatin lead to cell killing in head and neck squamous cell carcinoma patients, but adverse events and response to treatment are not the same in patients with similar clinicopathological aspects. The aim of this prospective study was to evaluate the roles of TP53 c.215G > C, FAS c.-671A > G, FAS c.-1378G > A, FASL c.-844 C > T, CASP3 c.-1191A > G, and CASP3 c.-182-247G > T single nucleotide...

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PMID: 32628088
DOI: 10.1177/1010428320938494

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