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Article

Susceptibility loci involved in cisplatin-induced cytotoxicity and apoptosis.

Pharmacogenetics and genomics - 1 Mar 2008

Shukla Sunita J, Duan Shiwei, Badner Judith A, Wu Xiaolin, Dolan M Eileen

Abstract excerpt

OBJECTIVES: Cisplatin is a widely used chemotherapeutic agent; however, nephrotoxicity and neuropathy are obstacles for drug efficacy. Little is known about the genes or genetic variants contributing to the risk of developing these toxicities or chemotherapeutic response. Thus, we have applied a cell-based model to identify and characterize previously unknown genes that may be involved in cellular susceptibility...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18300947
DOI: 10.1097/FPC.0b013e3282f5e605
PMCID: PMC2567113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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