XPD c.934G>A polymorphism of nucleotide excision repair pathway in outcome of head and neck squamous cell carcinoma patients treated with cisplatin chemoradiation.

doi:10.18632/oncotarget.7668

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Article

XPD c.934G>A polymorphism of nucleotide excision repair pathway in outcome of head and neck squamous cell carcinoma patients treated with cisplatin chemoradiation.

Oncotarget - 7 Mar 2017

Lopes-Aguiar Leisa, Costa Ericka Francislaine Dias, Nogueira Guilherme Augusto Silva, Lima Tathiane Regine Penna, Visacri Marília Berlofa, Pincinato Eder Carvalho, Calonga Luciane, Mariano Fernanda Viviane, de Almeida Milani Altemani Albina Messias, Altemani João Maurício Carrasco, Coutinho-Camillo Cláudia Malheiros, Ribeiro Alves Maria Almerinda Vieira Fernandes, Moriel Patrícia, Ramos Celso Dario, Chone Carlos Takahiro, Lima Carmen Silvia Passos

Abstract excerpt

This study aimed to investigate the associations of XPC c.2815A>C, XPD c.934G>A and c.2251A>C, XPF c.2505T>C and ERCC1 c.354C>T single nucleotide polymorphisms (SNPs) of nucleotide excision repair pathway in outcome of head and neck squamous cell carcinoma (HNSCC) patients treated with cisplatin (CDDP) chemoradiation. Patients with XPC c.2815AC or CC and XPD c.934GA or AA genotypes had 0.20 and 0.38 less chances...

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Identifiers

PMID: 26918827
DOI: 10.18632/oncotarget.7668
PMCID: PMC5369956

Genes

ERCC1
XPC

Variants

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