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Article

Intragenic and extragenic suppressors of temperature sensitive mutations in the replication initiation genes dnaD and dnaB of Bacillus subtilis.

PloS one - 26 Aug 2009

Rokop Megan E, Grossman Alan D

Abstract excerpt

BACKGROUND: The Bacillus subtilis genes dnaD and dnaB are essential for the initiation of DNA replication and are required for loading of the replicative helicase at the chromosomal origin of replication oriC. Wild type DnaD and DnaB interact weakly in vitro and this interaction has not been detected in vivo or in yeast two-hybrid assays. METHODOLOGY/PRINCIPAL FINDINGS: We isolated second site suppressors of the...

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Identifiers

PMID: 19707554
DOI: 10.1371/journal.pone.0006774
PMCID: PMC2727948

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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