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Article

Essential amino acids of Escherichia coli DnaC protein in an N-terminal domain interact with DnaB helicase.

The Journal of biological chemistry - 20 Jul 2001

Ludlam A V, McNatt M W, Carr K M, Kaguni J M

Abstract excerpt

Escherichia coli DnaC protein bound to ATP forms a complex with DnaB protein. To identify the domain of DnaC that interacts with DnaB, a genetic selection was used based on the lethal effect of induced dnaC expression and a model that inviability arises by the binding of DnaC to DnaB to inhibit replication fork movement. The analysis of dnaC alleles that preserved viability under elevated expression revealed an...

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PMID: 11333269
DOI: 10.1074/jbc.M101940200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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