Article
No association between cSHMT genotypes and the risk of breast cancer in the Nurses' Health Study.
European journal of clinical nutrition - 1 Jan 2010
Bentley A R, Raiszadeh F, Stover P J, Hunter D J, Hankinson S E, Cassano P A
Abstract excerpt
OBJECTIVES: Increased breast cancer risk has been observed with both low folate status and a functional polymorphism in methylenetetrahydrofolate reductase (MTHFR 677C --> T). Cytoplasmic serine hydroxymethyltransferase (cSHMT) affects the flow of one-carbon units through the folate metabolic network, but there is little research on a role for genetic variation in cSHMT in determining breast cancer risk. METHODS:...
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