Article
Breast cancer risk associated with multigenotypic polymorphisms in folate-metabolizing genes: a nested case-control study in Taiwan.
Anticancer research - 1 Jan 2000
Yu Cheng-Ping, Wu Mei-Hsuan, Chou Yu-Ching, Yang Tsan, You San-Lin, Chen Chien-Jen, Sun Chien-An
Abstract excerpt
AIM: The purpose of this study was to test the hypothesis that multigenotypic polymorphisms in the folate metabolic pathway, which may result in genomic instability and inbalance of estrogen metabolism, were associated with breast cancer risk. PATIENTS AND METHODS: A population-based nested case-control study of 109 cases with pathologically confirmed invasive breast cancer and 421 cancer-free controls was...
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