Article
Polymorphism of cytosolic serine hydroxymethyltransferase, estrogen and breast cancer risk among Chinese women in Taiwan.
Breast cancer research and treatment - 1 Sept 2008
Cheng Chun-Wen, Yu Jyh-Cherng, Huang Chiun-Sheng, Shieh Jia-Ching, Fu Yi-Ping, Wang Hsiao-Wei, Wu Pei-Ei, Shen Chen-Yang
Abstract excerpt
Cytosolic serine hydroxymethyltransferase (cSHMT) is key to intersection of folate-metabolic pathway, participating in the pyrimidine synthesis for DNA repair. Based on the hypothesis that variants of the cSHMT C1420T together with methionine synthase (MS A2756G) and 5,10-methylenetetrahydrofolat...
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