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Article

Polymorphism of cytosolic serine hydroxymethyltransferase and breast cancer risk: evidence from a meta-analysis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2014

Li Li, Ma Yin, Jin Chaohui, Zheng Qianru, Yang Lin

Abstract excerpt

One-carbon metabolism has been presumed to influence cancer pathogenesis. Cytosolic serine hydroxymethyltransferase (cSHMT) is a critical enzyme in one-carbon metabolism pathway. Until now, many studies have investigated the association between cSHMT (also named SHMT1) C1420T polymorphism and breast cancer risk. However, the results remained conflicting rather than conclusive. Literature search was conducted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24789272
DOI: 10.1007/s13277-014-1964-3

Genes

SHMT1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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