Article
Heterogeneity of HLA genetic factors in IDDM susceptibility.
Immunogenetics - 1 Jan 1990
Martell M, Marcadet A, Moine A, Boitard C, Deschamps I, Dausset J, Bach J F, Cohen D
Abstract excerpt
The association of certain HLA-D alleles with insulin-dependent diabetes mellitus (IDDM) is well known. One hundred and sixty-one non-related diabetic individuals and 142 non-related healthy controls were typed for the HLA DR-DQw-Dw association, using a restriction fragment length polymorphism (R...
Topics
- Alleles
- Base Sequence
- Diabetes Mellitus, Type 1
- Gene Amplification
- Genetic Predisposition to Disease
- Genotype
- HLA Antigens
- HLA-DQ Antigens
- HLA-DR Antigens
- Histocompatibility Testing
- Humans
- Molecular Sequence Data
- Oligonucleotide Probes
- Polymorphism, Restriction Fragment Length
