Article
Heterogeneity of HLA genetic factors in IDDM susceptibility.
Immunogenetics - 1 Jan 1990
Martell M, Marcadet A, Moine A, Boitard C, Deschamps I, Dausset J, Bach J F, Cohen D
Abstract excerpt
The association of certain HLA-D alleles with insulin-dependent diabetes mellitus (IDDM) is well known. One hundred and sixty-one non-related diabetic individuals and 142 non-related healthy controls were typed for the HLA DR-DQw-Dw association, using a restriction fragment length polymorphism (RFLP) typing method that combines three probe/enzyme systems: DRB/Taq I, DQB/Taq I, and DQB/Bam HI. Comparison of...
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