Article
Role of HLA class II alleles in Korean patients with IDDM.
Diabetes research and clinical practice - 1 Mar 1996
Lee H C, Ikegami H, Fujisawa T, Ogihara T, Park S W, Chung Y S, Park J O, Lee E J, Lim S K, Kim K R, Huh K B, Kim Y S, Lee D S, Kim D H, Fugisawa T
Abstract excerpt
MHC associations with IDDM in the Korean population were studied to investigate genetic susceptibility to this disorder. The frequencies of HLA-DR3, -DR4 and -DR9 were significantly higher in diabetic patients. However, the frequency of DR2 was significantly decreased in diabetic patients. DQA1*0301 and DQA1*0501 were positively and DQA1*0102 and DQA1*0201 negatively associated with IDDM. DQB1*0301 and DQB1*0601...
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