Susceptibility to IDDM in a Chinese population. Role of HLA class II alleles.

doi:10.2337/diab.41.8.914

Article

Susceptibility to IDDM in a Chinese population. Role of HLA class II alleles.

Diabetes - 1 Aug 1992

Penny M A, Jenkins D, Mijovic C H, Jacobs K H, Cavan D A, Yeung V T, Cockram C S, Hawkins B R, Fletcher J A, Barnett A H

Abstract excerpt

MHC associations with IDDM in a Chinese population were studied to investigate genetic susceptibility to the disorder. The frequency of HLA-DR3 was significantly higher in the diabetic patients (19/49 [38.7%] vs. control subjects, 11/105 [10.5%], Pc less than 1.3 x 10(-3), RR = 5.3 [CI 2.3-12.1])...

Topics

Alleles
Base Sequence
China
Diabetes Mellitus, Type 1
Disease Susceptibility
Gene Frequency
HLA-D Antigens
HLA-DQ Antigens
HLA-DR Antigens
Haplotypes
Humans
Molecular Sequence Data

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