Article
Physical mapping of a temperature-sensitive mutation of human cytomegalovirus by marker rescue.
Genetic analysis, techniques and applications - 1 Apr 1990
Dion M, Yelle J, Hamelin C
Abstract excerpt
Physical mapping of a temperature-sensitive (ts) mutation of human cytomegalovirus (HCMV) strain AD-169 was attempted here using cloned HindIII restriction endonuclease fragments and the mutant virus. The DNA-positive mutant tested (HCMV ts 1585) was successfully rescued by viral DNA sequences be...
Topics
- Chromosome Mapping
- Cloning, Molecular
- Cytomegalovirus
- Genes
- Genes, Viral
- Genetic Markers
- Humans
- Mutation
- Polymorphism, Restriction Fragment Length
- Temperature
- Transfection
- Viral Proteins
