Further characterization of ts1-8, a mutant of herpes simplex virus type 1.

doi:10.1016/0168-1702(91)90062-z

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Article

Further characterization of ts1-8, a mutant of herpes simplex virus type 1.

Virus research - 1 Jun 1991

Arko E F, Daksis J I, Chan V L

Abstract excerpt

Our initial characterization of a herpes simplex virus type 1, temperature sensitive host shutoff mutant, called ts1-8, revealed that it has a low plaquing efficiency and exhibits a defect in the shutoff of host polypeptide synthesis and host DNA replication at the nonpermissive temperature of 39...

Topics

Amino Acid Sequence
Animals
Cell Line
Cloning, Molecular
DNA Replication
Genetic Complementation Test
Molecular Sequence Data
Mutation
Protein Conformation
Simplexvirus
Temperature
Viral Envelope Proteins

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