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Article

Further characterization of ts1-8, a mutant of herpes simplex virus type 1.

Virus research - 1 Jun 1991

Arko E F, Daksis J I, Chan V L

Abstract excerpt

Our initial characterization of a herpes simplex virus type 1, temperature sensitive host shutoff mutant, called ts1-8, revealed that it has a low plaquing efficiency and exhibits a defect in the shutoff of host polypeptide synthesis and host DNA replication at the nonpermissive temperature of 39.5 degrees C. Using intratypic marker rescue experiments the ts plaquing mutation was mapped to a 557 bp region....

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Identifiers

PMID: 1656625
DOI: 10.1016/0168-1702(91)90062-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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