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Article

Zona occludens-2 is critical for blood-testis barrier integrity and male fertility.

Molecular biology of the cell - 1 Oct 2009

Xu Jianliang, Anuar Farhana, Ali Safiah Mohamed, Ng Mei Yong, Phua Dominic C Y, Hunziker Walter

Abstract excerpt

Tight junction integral membrane proteins such as claudins and occludin are tethered to the actin cytoskeleton by adaptor proteins, notably the closely related zonula occludens (ZO) proteins ZO-1, ZO-2, and ZO-3. All three ZO proteins have recently been inactivated in mice. Although ZO-3 knockout mice lack an obvious phenotype, animals deficient in ZO-1 or ZO-2 show early embryonic lethality. Here, we rescue the...

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Source

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Identifiers

PMID: 19692573
DOI: 10.1091/mbc.e08-12-1236
PMCID: PMC2762135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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