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Article

Androgens regulate the permeability of the blood–testis barrier

7 Nov 2005

Abstract excerpt

Within the mammalian testis, specialized tight junctions between somatic Sertoli cells create basal and apical polarity within the cells, restrict movement of molecules between cells, and separate the seminiferous epithelium into basal and adluminal compartments. These tight junctions form the basis of the blood-testis barrier, a structure whose function and dynamic regulation is poorly understood. In this study,...

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PMID: 16275920
DOI: 10.1073/pnas.0506084102

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