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Article

Blood–testis barrier and Sertoli cell function: lessons from SCCx43KO mice

10 Nov 2015

Abstract excerpt

The gap junction protein connexin43 (CX43) plays a vital role in mammalian spermatogenesis by allowing for direct cytoplasmic communication between neighbouring testicular cells. In addition, different publications suggest that CX43 in Sertoli cells (SC) might be important for blood-testis barrier (BTB) formation and BTB homeostasis. Thus, through the use of the Cre-LoxP recombination system, a transgenic mouse...

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PMID: 26556893
DOI: 10.1530/rep-15-0366

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Blood–testis barrier and Sertoli cell function: lessons from SCCx43KO micePMID 26556893Read ↗

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