Article
A fast SSP-PCR method for genotyping the ATP-binding cassette subfamily B member 1 gene C3435T and G2677T polymorphisms in Chinese transplant recipients.
Tumori - 1 Jan 2000
Wu Cun-Zao, Ni Xiao-Jie, Zheng Shao-Ling, Yang Yi-Rong, Xia Peng, Zeng Yan-Jun, Chen Bi-Cheng
Abstract excerpt
AIM: P-glycoprotein, the product of the ATP-binding cassette subfamily B member 1 (ABCB1) gene (or the so-called multidrug resistance 1 gene), is an ATP-driven efflux pump contributing to the pharmacokinetics as well as the pharmacokinetics of drugs that are P-glycoprotein substrates, such as tac...
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