A functional common polymorphism of the ABCB1 gene is associated with chronic kidney disease and hypertension in Chinese.

doi:10.1093/ajh/hpt126

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Article

A functional common polymorphism of the ABCB1 gene is associated with chronic kidney disease and hypertension in Chinese.

American journal of hypertension - 1 Dec 2013

Liu Ming, Li Yan, Citterio Lorena, Huang Qi-Fang, Zeng Wei-Fang, Sheng Chang-Sheng, Wei Fang-Fei, Dong Qian, Li Ge-Le, Kang Yuan-Yuan, Zhang Lu, Xu Ting-Yan, Li Jing-Jing, Song Jie, Manunta Paolo, Wang Ji-Guang

Abstract excerpt

BACKGROUND: Permeability glycoprotein is encoded by the ATP-binding cassette B1 gene (ABCB1) and is an extruder of toxic metabolites in the kidney. A functional common polymorphism (C3435T, rs1045642) in the human ABCB1 gene has been found to be associated with allograft outcome in kidney transplant patients. In this study, we investigated the association of the C3435T polymorphism with renal function and blood...

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Share to ATP Binding Cassette Transporter, Subfamily B

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Identifiers

PMID: 23926124
DOI: 10.1093/ajh/hpt126

Genes

ABCB1

Variants

rs1045642

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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