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Article

Effect of ABCB1 3435C>T Genetic Polymorphism on Pharmacokinetic Variables of Tacrolimus in Adult Renal Transplant Recipients: A Systematic Review and Meta-analysis.

Clinical therapeutics - 1 Oct 2020

Peng Wenxing, Lin Yang, Zhang Hao, Meng Kaikai

Abstract excerpt

PURPOSE: Tacrolimus is the substrate of multidrug-resistance 1 (ABCB1). However, the effect of ABCB1 C3435T polymorphism on pharmacokinetic variables of tacrolimus is controversial in different studies. This meta-analysis was conducted to explore the relationship between ABCB1 3435C>T genetic polymorphism and pharmacokinetic variables of tacrolimus. METHODS: A database search was conducted of PubMed, EMBASE,...

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Source

Identifiers

PMID: 32888708
DOI: 10.1016/j.clinthera.2020.07.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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