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Article

Direct and rapid genotyping of SLCO1B1 388A>G and 521T>C in human blood specimens using the SmartAmp-2 method.

The AAPS journal - 1 Apr 2013

Yoshida Kenta, Takano Junichi, Ishizu Yuri, Lezhava Alexander, Ieiri Ichiro, Maeda Kazuya, Hayashizaki Yoshihide, Sugiyama Yuichi

Abstract excerpt

Organic anion-transporting polypeptide (OATP) 1B1, encoded by the solute carrier organic anion transporter family member 1B1 (SLCO1B1) gene, mediates the active uptake of various organic anions into hepatocytes and determines their hepatic clearances as the first step in the detoxification pathway. Previous reports indicated that alterations in its function by drug-drug interactions or genetic polymorphisms...

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Identifiers

PMID: 23471819
DOI: 10.1208/s12248-013-9471-9
PMCID: PMC3675730

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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