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Article

Primer design for SNP genotyping based on allele-specific amplification-Application to organ transplantation pharmacogenomics.

Journal of pharmaceutical and biomedical analysis - 20 Mar 2017

Tortajada-Genaro Luis A, Puchades Rosa, Maquieira Ángel

Abstract excerpt

Diagnostic methods based on single nucleotide polymorphism (SNP) biomarkers are essential for the real adoption of personalized medicine. Allele specific amplification in a homogeneous format or combined to microarray hybridization are powerful approaches for SNP genotyping. However, primers must be properly selected to minimize cross-reactivity, dimer formation and nonspecific hybridization. This study presents...

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Share to ATP Binding Cassette Transporter, Subfamily B
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Multiplex Polymerase Chain Reaction

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Source

Identifiers

PMID: 28061365
DOI: 10.1016/j.jpba.2016.12.030

Genes

ABCB1
MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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