Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Direct biochemical measurements of signal relay during Dictyostelium development.

The Journal of biological chemistry - 4 Nov 2011

Das Satarupa, Rericha Erin C, Bagorda Anna, Parent Carole A

Abstract excerpt

Upon starvation, individual Dictyostelium discoideum cells enter a developmental program that leads to collective migration and the formation of a multicellular organism. The process is mediated by extracellular cAMP binding to the G protein-coupled cAMP receptor 1, which initiates a signaling cascade leading to the activation of adenylyl cyclase A (ACA), the synthesis and secretion of additional cAMP, and an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenylyl Cyclases
Share to Biochemistry
Share to Chemotaxis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cyclic AMP

Share to Cyclic AMP-Dependent Protein Kinases

Share to Dictyostelium

Share to Fluorescence Resonance Energy Transfer

Share to Receptors, Cyclic AMP

Source

Open in PubMed Open full text

Identifiers

PMID: 21911494
DOI: 10.1074/jbc.M111.284182
PMCID: PMC3207423

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Direct biochemical measurements of signal relay during Dictyostelium development.PMID 21911494Read ↗

TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium.Semantic proximity Read ↗

Molecular genetics of signal transduction in Dictyostelium.Semantic proximity Read ↗

Multiple roles for cAMP-dependent protein kinase during Dictyostelium development.Semantic proximity Read ↗

Protein kinase A regulates the Ras, Rap1 and TORC2 pathways in response to the chemoattractant cAMP in Dictyostelium.Semantic proximity Read ↗

A secondary disruption of the dmpA gene encoding a large membrane protein allows aggregation defective Dictyostelium rasC- cells to form multicellular structures.Semantic proximity Read ↗

Phosphorylation of actin-related protein 2 (Arp2) is required for normal development and cAMP chemotaxis in Dictyostelium.Semantic proximity Read ↗

RasC plays a role in transduction of temporal gradient information in the cyclic-AMP wave of Dictyostelium discoideum.Semantic proximity Read ↗

Assessment of development and chemotaxis in Dictyostelium discoideum mutants.Semantic proximity Read ↗

A novel Ras-interacting protein required for chemotaxis and cyclic adenosine monophosphate signal relay in Dictyostelium.Semantic proximity Read ↗

Chemoattractant stimulation of TORC2 is regulated by receptor/G protein-targeted inhibitory mechanisms that function upstream and independently of an essential GEF/Ras activation pathway in Dictyostelium.Semantic proximity Read ↗

A role for cAMP-dependent protein kinase A in early Dictyostelium development.Semantic proximity Read ↗

Genome-wide expression analyses of gene regulation during early development of Dictyostelium discoideum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.